电压噪声诱导的电可兴奋膜中的转变。
Voltage-noise-induced transitions in electrically excitable membranes.
作者信息
Horsthemke W, Lefever R
出版信息
Biophys J. 1981 Aug;35(2):415-32. doi: 10.1016/S0006-3495(81)84799-6.
Abstract
A quantitative study of the steady-state behavior of the sodium and potassium conductance for the Hodgkin-Huxley axon under the influence of an externally driven voltage noise is reported. The dichotomous Markov noise (random telegraph signal) considered allows for an exact evaluation of the stationary probability density of the conductances. Phase diagrams are constructed to represent the response of the system as a function of the amplitude and the correlation time of the noise. The results obtained for the Hodgkin-Huxley axon are compared with some molecular models used in the literature.
摘要
本文报道了在外部驱动电压噪声影响下，对霍奇金 - 赫胥黎轴突钠电导和钾电导稳态行为的定量研究。所考虑的二分马尔可夫噪声（随机电报信号）使得能够精确评估电导的稳态概率密度。构建相图以表示系统响应随噪声幅度和相关时间的变化。将霍奇金 - 赫胥黎轴突得到的结果与文献中使用的一些分子模型进行了比较。
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