Holden A V
Biol Cybern. 1980;38(1):1-8. doi: 10.1007/BF00337395.
Low calcium increases the excitability of neurones and can induce autorhythmicity in excitable cells. Numerical solutions of the Hodgkin-Huxley membrane equations, and numerical evaluations of the small-signal impedance and admittance are used to illustrate the increase in resonance produced by low [Ca2+]0. The resonant frequency may be located either by the peak of the amplitude of the impedance, or by the frequency at which the phase angle is zero for 1 : 1 entrained action potentials. Autorhythmicity is produced by any mechanism which increases the resonant peak of the amplitude of the membrane impedance.
低钙会增加神经元的兴奋性，并可在可兴奋细胞中诱导自动节律性。利用霍奇金-赫胥黎膜方程的数值解以及小信号阻抗和导纳的数值评估，来说明低[Ca2+]0所产生的共振增加。共振频率既可以通过阻抗幅度的峰值来确定，也可以通过1:1夹带动作电位时相角为零的频率来确定。任何增加膜阻抗幅度共振峰的机制都会产生自动节律性。
