接种和未接种疫苗的犊牛在感染牛支原体后滑膜中的免疫球蛋白和抗体
Synovial immunoglobulin and antibody in vaccinated and nonvaccinated calves challenged with Mycoplasma bovis.
作者信息
Chima J C, Wilkie B N, Nielsen K H, Ruhnke H L, Truscott R B, Maxie G, Chick B
出版信息
Can J Comp Med. 1981 Jan;45(1):92-6.
Intravenous injection of Mycoplasma bovis produced in calves arthritis with synovial infiltration of lymphocytes, macrophages and neutrophils. Necrosis was observed focally around blood vessels. Joint spaces contained fibrinopurulent exudate. Parenterally vaccinated calves had a markedly reduced frequency of arthritic joints. Immunoglobulin classes and specific antibody in joint fluids were quantitatively less than in sera but significantly greater in arthritic than in normal joints. The possible mechanisms of induction of joint fluid antibody are discussed.
静脉注射牛支原体可使犊牛发生关节炎，伴有淋巴细胞、巨噬细胞和中性粒细胞的滑膜浸润。在血管周围局部观察到坏死。关节间隙含有纤维蛋白脓性渗出物。经肠道外接种疫苗的犊牛患关节炎关节的频率明显降低。关节液中的免疫球蛋白类别和特异性抗体在数量上低于血清，但在患关节炎的关节中明显高于正常关节。本文讨论了关节液抗体诱导的可能机制。
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