Mack T M, Paganini-Hill A
Cancer. 1981 Mar 15;47(6 Suppl):1474-84. doi: 10.1002/1097-0142(19810315)47:6+<1474::aid-cncr2820471406>3.0.co;2-4.
The characteristics of the 3614 Los Angeles County residents in whom cancer of the exocrine pancreas was diagnosed during the period 1972-1977 were compared with those of all county residents and patients in whom any cancer was diagnosed during the same period. Seventy-nine percent of the diagnoses had been pathologically verified. This disease still preferentially afflicts the old, the black, and men, although the differences in risk with factors other than age are modest. The disease is not evenly distributed by social class, or over time, although it is not clear that the observed differences reflect etiology. The distributions with respect to important categories of occupation and industry, religion, marital status, geography of residence, and birthplace were rather uniform. Although there is no obvious explanation for any of several unexpected minor inequities in the pattern of incidence, there is no compelling evidence to support any specific environmental cause. There is substantial evidence which is inconsistent with those environmental hypotheses that have been proposed previously.
对1972年至1977年期间在洛杉矶县被诊断患有外分泌胰腺癌的3614名居民的特征，与该县所有居民以及同期被诊断患有任何癌症的患者的特征进行了比较。79%的诊断已通过病理证实。这种疾病仍然优先影响老年人、黑人以及男性，尽管除年龄外其他因素导致的风险差异不大。这种疾病在社会阶层或不同时间段的分布并不均匀，尽管尚不清楚观察到的差异是否反映病因。在重要的职业和行业类别、宗教、婚姻状况、居住地理位置和出生地方面的分布相当均匀。尽管对于发病率模式中几个意外的小不平等现象没有明显的解释，但也没有令人信服的证据支持任何特定的环境病因。有大量证据与先前提出的那些环境假说不一致。
