Identification of a reactive metabolite of the mutagen, 2-amino-3-methylimidazolo[4,5-f]quinoline. - Suppr | 超能文献

Identification of a reactive metabolite of the mutagen, 2-amino-3-methylimidazolo[4,5-f]quinoline.

作者信息

Okamoto T, Shudo K, Hashimoto Y, Kosuge T, Sugimura T, Nishimura S

出版信息

Chem Pharm Bull (Tokyo). 1981 Feb;29(2):590-3. doi: 10.1248/cpb.29.590.

DOI:10.1248/cpb.29.590

Abstract

摘要

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Mutagenic activation of 2-amino-3-methylimidazo[4,5-f]-quinoline (IQ) and 2-amino-3,4-dimethylimidazo[4,5-f]-quinoline (MeIQ) by subcellular fractions and cells isolated from small intestine, kidney and liver of the rat.大鼠小肠、肾脏和肝脏中分离出的亚细胞组分和细胞对2-氨基-3-甲基咪唑并[4,5-f]喹啉（IQ）和2-氨基-3,4-二甲基咪唑并[4,5-f]喹啉（MeIQ）的诱变激活作用。

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