Chotoev Zh A, Nanaeva M T
Farmakol Toksikol. 1981 Mar-Apr;44(2):159-62.
The effect of intraperitoneal administration of sodium hydroxybutyrate on oxidative phosphorylation in mitochondria and on the activity of glucoso-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase in the cardiac muscle was studied under alpine conditions (3200 m above the sea level). The drug was shown to increase the conjugation of oxidation with phosphorylation, to potentiate the activity of the test enzymes of the pentose cycle in the heart of the animals with one-month long adaptation to high-altitude hypoxia.
在海拔3200米的高原条件下，研究了腹腔注射羟基丁酸钠对线粒体氧化磷酸化以及对心肌中葡萄糖-6-磷酸脱氢酶和6-磷酸葡萄糖酸脱氢酶活性的影响。结果表明，对于已对高原低氧适应了一个月的动物，该药物可增强氧化与磷酸化的偶联作用，并增强心脏中戊糖循环测试酶的活性。
