[Evaluation of blood flow heterogeneity in the limbs of dogs by hydrogen clearance in venous blood].

On the basis of Fick's principle, concept of the tissue blood flow heterogeneity and H2 concentration changes in arterial blood after short-term hydrogen inhalation, a method of calculating some blood flow indices in the limbs by H2 content desaturation changes in venous blood was developed. The suggested method allows to calculate the mean regional flow rate, its compartmentation, and blood flow/tissue volume ratio for the measured components of the regional blood flow. In the limb tissue of anesthetized dogs, two components of the blood flow with the rates 0.79 +/- 0.07 and 0.12 +/- 0.01 were measured, their mean rate being 0.16 +/- 0.01 ml/min. g. The share of the "slow" component in total blood flow and tissue volume was 70 +/- 3 and 93 +/- 1 per cent respectively.