Thakur A S, Prezioso U, Marchevsky N
Am J Vet Res. 1978 May;39(5):859-60.
A study was made on 120 dogs to evaluate the effectiveness of droncit against Echinococcus granulous infection. The drug was administered orally in tablet form at dose rates of 1.25, 2.5, 5.0,and 10.0 mg/kg of body weight against immature stages of the parasite and at a dose rate of 5.0 mg/kg against gravid worms. Droncit was found to be 100% effective against both immature and gravid worms at the dose rate of 5.0 mg/kg. Adverse reactions were not observed in the treated dogs, and no risk was involved in administering the drug. The use of droncit in hydatidosis control programs in discussed.
对120只狗进行了一项研究,以评估丙硫咪唑对细粒棘球绦虫感染的疗效。该药物以片剂形式口服,针对寄生虫未成熟阶段的剂量率为1.25、2.5、5.0和10.0毫克/千克体重,针对妊娠虫的剂量率为5.0毫克/千克。发现丙硫咪唑在5.0毫克/千克的剂量率下对未成熟和妊娠虫均有100%的疗效。在接受治疗的狗中未观察到不良反应,给药也没有风险。文中讨论了丙硫咪唑在包虫病控制项目中的应用。