Gemmell M A, Johnstone P D, Oudemans G
Res Vet Sci. 1977 Jul;23(1):121-3.
The effect of praziquantel on Echinococcus granulosus, Taenia hydatigena and T ovis was investigated in a trial involving 360 dogs. The drug was found to be highly toxic to tapeworms. Few dogs remained infected after a single treatment within the range of dose rates tested (0-31 mg/kg to 10-0 mg/kg body weight). No toxicity to dogs was observed.
在一项涉及360只狗的试验中,研究了吡喹酮对细粒棘球绦虫、泡状带绦虫和绵羊绦虫的作用。发现该药物对绦虫具有高毒性。在测试的剂量率范围内(0 - 31毫克/千克至10 - 0毫克/千克体重)单次治疗后,很少有狗仍被感染。未观察到对狗的毒性。