Andersen F L, Crellin J R, Cox D D
Am J Vet Res. 1981 Nov;42(11):1978-9.
Efficacy of an injectable formulation of praziquantel (given IM at a dosage of 5 mg/kg of body weight) against immature Echinococcus multilocularis was studied in 18 experimentally infected dogs and 22 experimentally infected cats. There were no worms recovered at necropsy from any of the treated hosts. However, whereas E multilocularis worms were recovered from all nontreated control dogs (n = 9; min-max 15-1,840, mean 483), such tapeworms were recovered from only k6 of the 11 nontreated control cats (min-max 2-820; overall mean 123.4). The study demonstrates 100% clearance of E multilocularis by praziquantel in experimentally infected dogs and cats, and shows that cats are not as suitable as experimental hosts for this parasite as are dogs.
在18只实验感染的犬和22只实验感染的猫中，研究了吡喹酮注射制剂（以5毫克/千克体重的剂量肌肉注射）对未成熟多房棘球绦虫的疗效。在尸检时，未从任何一只接受治疗的宿主中检获虫体。然而，虽然从所有未治疗的对照犬（n = 9；最小 - 最大15 - 1840，平均483）中检获了多房棘球绦虫，但在11只未治疗的对照猫中，仅从6只猫中检获了这种绦虫（最小 - 最大2 - 820；总体平均123.4）。该研究表明，吡喹酮在实验感染的犬和猫中对多房棘球绦虫的清除率为100%，并且表明猫作为该寄生虫的实验宿主不如犬合适。
