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J Clin Pathol. 1981 Aug;34(8):902-5. doi: 10.1136/jcp.34.8.902.
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液体枸橼酸钠和干燥枸橼酸钠作为血栓试验及凝血酶原时间测定抗凝剂的比较

Comparison of liquid and dried sodium citrate as the anticoagulant for Thrombotest and prothrombin time estimations.

作者信息

Hoctor D, Bottomley J, Hyde K, Gowenlock A H, Maciver J E

出版信息

J Clin Pathol. 1981 Aug;34(8):902-5. doi: 10.1136/jcp.34.8.902.

DOI:10.1136/jcp.34.8.902
PMID:7276209
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC493976/
Abstract

Samples which are taken for the Quick one-stage prothrombin time estimation for the control of patients receiving oral anticoagulant treatment are by convention taken into liquid sodium citrate anticoagulant. Dried sodium citrate has been rejected on the grounds that excessive haemolysis causes activation of clotting factors and therefore falsely short clotting times. Tests were performed with both liquid and dried sodium citrate as an anticoagulant for prothrombin time and Thrombotest. No clinically significant difference between the values given by the two anticoagulants was observed.

摘要

为控制接受口服抗凝治疗的患者而采集用于快速一步法凝血酶原时间估算的样本，按照惯例采集到液体枸橼酸钠抗凝剂中。干燥枸橼酸钠已被摒弃，理由是过度溶血会导致凝血因子激活，从而使凝血时间错误地缩短。对液体和干燥枸橼酸钠作为凝血酶原时间和血栓试验的抗凝剂进行了测试。未观察到两种抗凝剂给出的值之间存在临床显著差异。