Czekala N M, Hodges J K, Lasley B L
J Med Primatol. 1981;10(1):1-15. doi: 10.1159/000460046.
Immunoreactive estrogen and luteinizing hormone/chorionic gonadotropin (LH/CG) bioactivity have been measured throughout pregnancy in diverse primate species with a sample methodological approach utilizing small volumes of urine collected randomly. Total immunoreactive estrogen levels and the relative abundance of component estrogens (estrone, estradiol and estriol) at various stages of gestation were compared in the human, orangutan, pygmy chimpanzee, Douc langur and capuchin. Measurement of urinary LH/CG bioactivity enables an earlier detection of pregnancy when compared to the nonhuman primate pregnancy test. The methods described provide a practical and non-stressful way to detect and monitor pregnancy in widely divergent primate species.
在整个孕期，采用一种样本方法学途径，即随机收集少量尿液，对多种灵长类物种的免疫反应性雌激素和促黄体生成素/绒毛膜促性腺激素（LH/CG）生物活性进行了测定。在人类、猩猩、倭黑猩猩、白臀叶猴和卷尾猴中，比较了妊娠各阶段的总免疫反应性雌激素水平以及各组分雌激素（雌酮、雌二醇和雌三醇）的相对丰度。与非人灵长类动物妊娠试验相比，测量尿LH/CG生物活性能够更早地检测到妊娠。所描述的方法为在广泛不同的灵长类物种中检测和监测妊娠提供了一种实用且无应激的方式。
