甲状旁腺腺瘤与轻链骨髓瘤。

Chisholm R C, Weaver Y J, Chung E B, Townsend J L

J Natl Med Assoc. 1981 Sep;73(9):875-80.

An elderly patient with simultaneous hyperparathyroidism and light chain myeloma is described. The patient presented with hypercalcemia, bone pain, pathologic fractures, and cystic and lytic bone lesions. The problems of diagnosis and management are discussed. It is recommended that elderly patients with hypercalcemia and bone lesions should have not only diagnostic studies for hyperparathyroidism but also serum and urine immunoelectrophoresis to detect multiple myeloma or plasma cell neoplastic variants. Surgery is indicated for the hyperparathyroidism. Chemotherapy and localized radiotherapy usually control the myelomatous disease.

本文描述了一位同时患有甲状旁腺功能亢进和轻链骨髓瘤的老年患者。该患者表现为高钙血症、骨痛、病理性骨折以及囊性和溶解性骨病变。文中讨论了诊断和治疗问题。建议患有高钙血症和骨病变的老年患者不仅要进行甲状旁腺功能亢进的诊断性检查，还要进行血清和尿液免疫电泳以检测多发性骨髓瘤或浆细胞肿瘤变体。对于甲状旁腺功能亢进，手术治疗是必要的。化疗和局部放疗通常可控制骨髓瘤疾病。