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抑制商数。一种解释最低抑菌浓度数据的方法。

The inhibitory quotient. A method for interpreting minimum inhibitory concentration data.

作者信息

Ellner P D, Neu H C

出版信息

JAMA. 1981 Oct 2;246(14):1575-8. doi: 10.1001/jama.246.14.1575.

DOI:10.1001/jama.246.14.1575
PMID:7277631
Abstract

A method for reporting minimum inhibitory concentration (MIC) data that facilitates interpretation by the clinician unfamiliar with clinically achievable drug levels is described. This system uses the inhibitory quotient, which is a number reflecting the multiple of the MIC that would be achieved. Inhibitory quotients are determined for blood, urine, bile, and CSF and reflect achievable drug levels in those body fluids. The use of inhibitory quotients can be extremely helpful to the physician in the rational selection of an appropriate antimicrobial agent.

摘要

本文描述了一种报告最低抑菌浓度（MIC）数据的方法，该方法便于不熟悉临床可达到药物水平的临床医生进行解读。该系统使用抑制商数，它是一个反映可达到的MIC倍数的数字。针对血液、尿液、胆汁和脑脊液确定抑制商数，其反映了这些体液中可达到的药物水平。抑制商数的使用对医生合理选择合适的抗菌药物非常有帮助。

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