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1
Hypomagnesaemic hypocalcaemia with hypokalaemia caused by treatment with high dose gentamicin.高剂量庆大霉素治疗所致的低镁血症性低钙血症伴低钾血症
Arch Dis Child. 1978 Oct;53(10):817-20. doi: 10.1136/adc.53.10.817.
2
Hypomagnesemic hypocalcemia secondary to renal magnesium wasting.继发于肾性镁消耗的低镁血症性低钙血症
Ann Intern Med. 1975 May;82(5):646-9. doi: 10.7326/0003-4819-82-5-646.
3
Symptomatic hypomagnesemia associated with gentamicin therapy.与庆大霉素治疗相关的症状性低镁血症。
Magnes Trace Elem. 1990;9(1):54-60.
4
Symptomatic hypomagnesemia associated with gentamicin therapy.
Nephron. 1979;23(1):50-2. doi: 10.1159/000181606.
5
Hypomagnesemia associated with gentamicin therapy.
Drug Intell Clin Pharm. 1984 Jul-Aug;18(7-8):596-8. doi: 10.1177/106002808401800707.
6
Hypomagnesaemia leading to parathyroid dysfunction, hypocalcaemia, and hypokalaemia as a complication of long-term treatment with a proton pump inhibitor - a literature review.长期使用质子泵抑制剂导致低镁血症进而引发甲状旁腺功能障碍、低钙血症和低钾血症：文献综述。
Endokrynol Pol. 2024;75(4):359-365. doi: 10.5603/ep.98576.
7
Symptomatic hypocalcemia and hypomagnesemia due to gentamicin therapy in an 8-year-old girl.
Turk J Pediatr. 1982 Oct-Dec;24(4):267-9.
8
Omeprazole-induced hypomagnesaemia, causing renal tubular acidosis with hypokalaemia, hypocalcaemia, hyperlactacidaemia and hyperammonaemia.奥美拉唑引起的低镁血症，导致肾小管性酸中毒伴低钾血症、低钙血症、高乳酸血症和高血氨血症。
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[Hypokalemia, hypocalcemia and hypomagnesemia associated with gentamicin].[庆大霉素相关的低钾血症、低钙血症和低镁血症]
Harefuah. 1980 Aug;99(3-4):77-8.
10
[An unknown but potentially serious side effect of proton pump inhibitors: hypomagnesaemia].[质子泵抑制剂一种未知但可能严重的副作用：低镁血症]
Ned Tijdschr Geneeskd. 2009;153:A711.

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Colistin-induced Bartter-like Syndrome: Ponder before Treatment!黏菌素诱发的类巴特综合征：治疗前需慎重考虑！
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Drug-induced hypomagnesaemia : scope and management.药物性低镁血症：范围与管理
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Drug-induced electrolyte abnormalities.药物性电解质异常
Drugs. 1982 Sep;24(3):207-28. doi: 10.2165/00003495-198224030-00002.

本文引用的文献

1
Experimental human magnesium depletion.人体镁缺乏实验
Medicine (Baltimore). 1969 Jan;48(1):61-85. doi: 10.1097/00005792-196901000-00003.
2
Drug-induced secondary hyperaldosteronism in patients with pulmonary tuberculosis.
Q J Med. 1970 Apr;39(154):299-315.
3
Hypomagnesemic hypocalcemia secondary to renal magnesium wasting.继发于肾性镁消耗的低镁血症性低钙血症
Ann Intern Med. 1975 May;82(5):646-9. doi: 10.7326/0003-4819-82-5-646.
4
Functional hypoparathyroidism and parathyroid hormone end-organ resistance in human magnesium deficiency.人类镁缺乏时的功能性甲状旁腺功能减退和甲状旁腺激素终末器官抵抗
Clin Endocrinol (Oxf). 1976 May;5(3):209-24. doi: 10.1111/j.1365-2265.1976.tb01947.x.
5
Experimental aminoglycoside nephrotoxicity.实验性氨基糖苷类肾毒性
J Lab Clin Med. 1975 Aug;86(2):213-20.
6
Gentamicin persistence in the body.庆大霉素在体内的持续存在。
Lancet. 1977 Feb 26;1(8009):486. doi: 10.1016/s0140-6736(77)91973-0.
7
Letter: Prolonged excretion of gentamicin in a patient with umimpaired renal function.信函：庆大霉素在肾功能未受损患者中的长期排泄。
Lancet. 1975 Feb 1;1(7901):286. doi: 10.1016/s0140-6736(75)91197-6.

高剂量庆大霉素治疗所致的低镁血症性低钙血症伴低钾血症

Hypomagnesaemic hypocalcaemia with hypokalaemia caused by treatment with high dose gentamicin.

作者信息

Kelnar C J, Taor W S, Reynolds D J, Smith D R, Slavin B M, Brook C G

出版信息

Arch Dis Child. 1978 Oct;53(10):817-20. doi: 10.1136/adc.53.10.817.

DOI:10.1136/adc.53.10.817
PMID:727798
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1545406/
Abstract

A 12-year-old boy developed renal wasting of magnesium, calcium, and potassium, with secondary hypomagnesaemia, hypocalcaemia, and hypokalaaemia (without hyperaldosteronism) after treatment with 14 400 mg gentamicin over 4 months. Gentamicin should not be given for prolonged courses if less toxic antibiotics are suitable. If it used, plasma magnesium, calcium, and potassium levels should be monitored during and after treatment.

摘要

一名12岁男孩在4个月内接受了14400毫克庆大霉素治疗后，出现了镁、钙和钾的肾性流失，继发低镁血症、低钙血症和低钾血症（无醛固酮增多症）。如果有毒性较小的抗生素可用，则不应长期使用庆大霉素。如果使用了庆大霉素，在治疗期间和治疗后应监测血浆镁、钙和钾水平。