Skutsch G M
Med Hypotheses. 1981 Jun;7(6):737-46. doi: 10.1016/0306-9877(81)90085-2.
Starting from the fact that there are abnormal sweat K+ /Na+ ratios in both manics and depressives an attempt has been made to explain manic depression in terms of a disorder of the circadian rhythm of the adrenal glands. This, in turn, it is suggested, is caused by a defective circadian rhythm of central dopamine brought about by its having an abnormal response to ambient temperature change.
基于躁狂症患者和抑郁症患者汗液中钾离子/钠离子比例均异常这一事实，人们尝试从肾上腺昼夜节律紊乱的角度来解释躁狂抑郁症。进而有人提出，这是由中枢多巴胺的昼夜节律缺陷所致，而中枢多巴胺对环境温度变化反应异常导致了这种缺陷。
