Perris C
Arch Gen Psychiatry. 1978 Mar;35(3):438-31. doi: 10.1001/archpsyc.1978.01770270078007.
The possible morbidity suppressive effect of lithium carbonate on cycloid psychosis has been investigated in 30 patients who had suffered from recurrent episodes. The patients were followed up from 1 to 8.5 years after starting lithium treatment. In the analysis, patients were divided into those who took lithium regularly and those who took it irregularly, the division being based on the lithium plasma levels at the periodic control examinations. The study, which is of the so-called mirror tye, supports the hypothesis that well-conducted lithium maintenance treatment has a favorable morbidity suppressive effect in patients suffering from cycloid psychosis.
我们对30例患有复发性循环型精神病的患者进行了研究，以探讨碳酸锂对该病可能存在的发病率抑制作用。这些患者在开始锂盐治疗后接受了1至8.5年的随访。在分析过程中，根据定期对照检查时的血浆锂水平，将患者分为规律服用锂盐组和不规律服用锂盐组。这项所谓的镜像式研究支持了这样一种假设，即对于患有循环型精神病的患者，规范的锂盐维持治疗具有良好的发病率抑制作用。
