Gromov L A, Krivorotov S V, Skryma R N
Neirofiziologiia. 1981;13(3):332-4.
Intra- and extracellular influence of morphine was studied on isolated snail neurons by the method of intracellular dialysis under conditions of membrane potential clamp. It is found that morphine induces an inward current in all the investigated cells, it also changes the sensitiveness of the membrane to acetylcholine depending on the type of cell under investigation. It is suggested that such influence in normally functioning cells may be realized by endogenic peptides-analgetics.
在膜电位钳制条件下,采用细胞内透析法研究了吗啡对分离的蜗牛神经元的细胞内和细胞外影响。发现吗啡在所有被研究的细胞中都诱导出内向电流,并且根据所研究细胞的类型,它还会改变膜对乙酰胆碱的敏感性。有人提出,在正常功能的细胞中,这种影响可能是由内源性肽类镇痛药实现的。