Krebs H, Baca I
Arch Orthop Trauma Surg (1978). 1978 Oct 27;92(4):237-41. doi: 10.1007/BF02341805.
In connection with our observations of three patients with giant-cell tumors of the sacrum a description of this disease is given reviewing the 51 cases which have been published world-wide. As other tumors of the sacrococcygeal region the giant-cell tumor has no significant symptoms which would allow a differential diagnosis. Pain in the sacral region often radiating to both legs is the predominant symptom. Surgical intervention is the treatment of choice. To obtain a complete excision of the tumor with minimal damage to nervous structures the abdominal, sacral or abdomino-sacral route is recommended by several authors. The prognosis is dubious because a total removal is usually not feasable, and there is a high risk of recurrence and malignant degeneration.
结合我们对三例骶骨巨细胞瘤患者的观察，本文对该病进行了描述，并回顾了全球已发表的51例病例。与其他骶尾区域肿瘤一样，巨细胞瘤没有明显症状可供鉴别诊断。骶部疼痛并常放射至双腿是主要症状。手术干预是首选治疗方法。为了在对神经结构损伤最小的情况下完整切除肿瘤，多位作者推荐采用腹部、骶部或腹骶联合入路。预后不确定，因为通常无法实现完全切除，且复发和恶性变风险高。
