Keller U, Wüthrich B
Schweiz Med Wochenschr. 1981 Jan 24;111(4):112-7.
77 patients with suspected allergic rhinitis to inhalative allergens were studied. Skin tests, RAST determinations and nasal provocation tests, performed by placing a cotton-pledge with aqueous allergen and by "passive anterior rhinomanometry" (PAR), were carried out. This latter test was evaluated by determining nasal resistance and by measuring the temperature variations before and after allergen aerosol inhalation with use of a Heyer-PAR rhinomanometer-sprayer by the method of van Dishoeck. Among 30 hay-fever patients with positive prick tests to grasses or to birch pollens, the overall agreement of PAR with the other allergological diagnostic methods was 90 +/- 5%. Evaluation of a further 47 patients with perennial rhinopathy and suspected allergy to house dust, housedust mite and different molds showed that PAR serves to clarify the allergy diagnosis more reliably than the other methods. The advantages and the negative aspects of PAR are briefly discussed.
对77例疑似吸入性过敏原过敏性鼻炎患者进行了研究。进行了皮肤试验、放射性变应原吸附试验(RAST)测定以及鼻激发试验,鼻激发试验通过放置含有水性过敏原的棉拭子以及采用“被动前鼻测压法”(PAR)来进行。后一种试验通过使用Heyer - PAR鼻测压喷雾器,采用范迪肖克方法测定鼻阻力以及测量过敏原气雾剂吸入前后的温度变化来进行评估。在30例对草或桦树花粉点刺试验呈阳性的花粉症患者中,PAR与其他变应性疾病诊断方法的总体一致性为90±5%。对另外47例患有常年性鼻病且疑似对屋尘、屋尘螨和不同霉菌过敏的患者进行评估表明,PAR比其他方法更能可靠地明确过敏诊断。简要讨论了PAR的优点和不足之处。