Rhyne L, Rambo W M
South Med J. 1981 Sep;74(9):1043-4. doi: 10.1097/00007611-198109000-00004.
Necrotizing fasciitis is a lethal and insidious disease with a high mortality. It often begins in areas exposed to fecal or urinary contamination, and about 70% of cases occur in diabetics. A high index of suspicion should be maintained in diabetic patients with an infection in the perineum, genitalia, thigh, or buttocks. Factors leading to a poor prognosis are increased age and extent of disease at the time of diagnosis, especially myonecrosis. Therapy is primarily radical surgical debridement with adjunctive antibiotic therapy.
坏死性筋膜炎是一种致命且隐匿的疾病，死亡率很高。它通常始于暴露于粪便或尿液污染的部位，约70%的病例发生在糖尿病患者中。对于患有会阴部、生殖器、大腿或臀部感染的糖尿病患者，应保持高度的怀疑指数。导致预后不良的因素包括年龄增加和诊断时疾病的范围，尤其是肌坏死。治疗主要是进行根治性手术清创并辅以抗生素治疗。
