Ou L F, Yeh F L, Fang R H, Yu K W
Department of Surgery, Veterans General Hospital-Taipei, Taiwan, R.O.C.
Zhonghua Yi Xue Za Zhi (Taipei). 1993 Apr;51(4):271-5.
Necrotizing fasciitis is a relatively rare soft tissue infection that is characterized by rapidly widespread necrosis of the fascia and subcutaneous tissue. Fifty-eight cases were reviewed over a 5.5-year period. The majority of wound cultures were polymicrobial and single culture rate was 18.6%. The facultative organisms were most frequently recovered. The most frequently discovered bacteria were E. coli, Proteus mirabilis, Klebsiella pneumoniae, Staphylococcus aureus and group D enterococcus. The overall mortality rate was 48.3%. Early recognition, serial radical surgical debridement and strong and appropriate antibiotics were essential for survival.
坏死性筋膜炎是一种相对罕见的软组织感染，其特征为筋膜和皮下组织迅速广泛坏死。在5.5年的时间里回顾了58例病例。大多数伤口培养为多种微生物感染，单一培养率为18.6%。最常分离出兼性菌。最常发现的细菌是大肠杆菌、奇异变形杆菌、肺炎克雷伯菌、金黄色葡萄球菌和D组肠球菌。总死亡率为48.3%。早期识别、连续彻底的外科清创以及强效且合适的抗生素是生存的关键。
