Moodley G P
S Afr Med J. 1981 Oct 3;60(14):545-7.
The value of determination of the micro-erythrocyte sedimentation rate (ESR), testing for the presence of serum C-reactive protein (CRP) and the total white cell count (WCC) has been assessed in neonates and children, both healthy and in disease states. The results show that collective and maximum use of all three investigations aids diagnosis because these tests are simple, quick, cheap and easy to perform. Furthermore, the study has demonstrated that compared with a high ESR and WCC, the presence of CRP was the best single indicator of infection. The CRP test has the greatest predictive value and sensitivity in that it indicates the intensity of an infection as well as the patient's response to therapy.
微红细胞沉降率(ESR)测定、血清C反应蛋白(CRP)检测及白细胞总数(WCC)检测在新生儿和儿童健康及疾病状态下的价值已得到评估。结果表明,综合并最大限度地利用这三项检查有助于诊断,因为这些检查简单、快速、廉价且易于操作。此外,研究表明,与高ESR和WCC相比,CRP的存在是感染的最佳单一指标。CRP检测具有最大的预测价值和敏感性,因为它不仅能表明感染的强度,还能显示患者对治疗的反应。