体外血红素降解的机制。形成血红素-氧复合物的动力学证据。
The mechanism of haem degradation in vitro. Kinetic evidence for the formation of a haem-oxygen complex.
作者信息
Brown S B, Thomas S E
出版信息
Biochem J. 1978 Oct 15;176(1):327-30. doi: 10.1042/bj1760327.
Abstract
The rate of haem degradation in aqueous pyridine shows a saturation dependence on O2 concentration. CO competitively inhibits the reaction. This is evidence for formation of an iron-O2 complex and is consistent with an intramolecular pathway for haem degradation.
摘要
在吡啶水溶液中，血红素的降解速率对氧气浓度呈现出饱和依赖性。一氧化碳竞争性抑制该反应。这是形成铁 - 氧络合物的证据，并且与血红素降解的分子内途径相一致。
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