Takeuchi K
No To Shinkei. 1978 Nov;30(11):1183-91.
An unverified disease called "Moyamoya Disease" or "Spontaneous occlusion of the circle of Willis" has been recently reported as a disease entity by some Japanese researchers. Since the first report of this disease by Shimizu and the author in 1955, many cases have been reported not only in Japan but in many countries outside Japan. It has been already clarified either clinically or pathologically, that, in the Moyamoya Disease, the most important finding is the basal arterial occlusive change of unknown etiology and the Moyamoya Phenomenon is only nonspecific neuroradiological change as the extraordinary dilated collaterals via the striate arteries, perforators etc. However, the real cause of the arterial obstruction is still obscure in the so-called "true Moyamoya Disease". Further studies will be necessary in order to establish a new clinical entity related to the Moyamoya Disease. However, under existing situations, the Moyamoya Disease must be strictly differentiated from the Moyamoya Phenomenon which can be frequently observed among cases with basal occlusion of known and unknown origin.
一种名为“烟雾病”或“大脑 Willis 环自发性闭塞”的未经证实的疾病，最近被一些日本研究人员作为一种疾病实体进行了报道。自 1955 年清水和作者首次报道这种疾病以来，不仅在日本，而且在日本以外的许多国家都报道了许多病例。在烟雾病中，无论是在临床上还是在病理上，已经明确最重要的发现是病因不明的基底动脉闭塞性改变，而烟雾现象只是通过纹状动脉、穿支动脉等异常扩张的侧支循环所表现出的非特异性神经放射学改变。然而，在所谓的“真性烟雾病”中，动脉阻塞的真正原因仍然不明。为了建立一种与烟雾病相关的新的临床实体，还需要进一步研究。然而，在现有情况下，必须将烟雾病与在已知和未知病因的基底动脉闭塞病例中经常观察到的烟雾现象严格区分开来。
