合成皮质类固醇药物对肾上腺皮质的抑制作用：泼尼松龙与倍他米松的比较研究。
Adrenocortical suppression by synthetic corticosteroid drugs: a comparative study of prednisolone and betamethasone.
作者信息
Downie W W, Dixon J S, Lowe J R, Rhind V M, Leatham P A, Pickup M E
出版信息
Br J Clin Pharmacol. 1978 Nov;6(5):397-9. doi: 10.1111/j.1365-2125.1978.tb04603.x.
Abstract
1 Single-dose studies were conducted to investigate the relative potency of prednisolone and betamethasone in suppressing adrenocortical function. 2 Betamethasone produced more profound suppression of plasma cortisol than an equivalent anti-inflammatory dose of prednisolone.
摘要
1 进行了单剂量研究，以调查泼尼松龙和倍他米松在抑制肾上腺皮质功能方面的相对效力。2 与等效抗炎剂量的泼尼松龙相比，倍他米松对血浆皮质醇的抑制作用更强。
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Adrenocortical suppression by synthetic corticosteroid drugs: a comparative study of prednisolone and betamethasone.合成皮质类固醇药物对肾上腺皮质的抑制作用：泼尼松龙与倍他米松的比较研究。
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本文引用的文献
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A simple fluorimetric method for the estimation of free 11-hydroxycorticoids in human plasma.一种用于测定人血浆中游离11-羟基皮质类固醇的简易荧光法。
J Clin Pathol. 1962 Jul;15(4):374-9. doi: 10.1136/jcp.15.4.374.
2
Corticosteroid therapy in rheumatoid arthritis; comparative study of effects of prednisone and prednisolone, methylprednisolone, triamcinolone, and dexamethasone.类风湿关节炎中的皮质类固醇疗法；泼尼松、泼尼松龙、甲泼尼龙、曲安奈德和地塞米松疗效的比较研究。
J Am Med Assoc. 1959 Jul 11;170(11):1253-60. doi: 10.1001/jama.1959.03010110001001.
3
Decreased clearance of prednisolone, a factor in the development of corticosteroid side effects.泼尼松龙清除率降低，这是皮质类固醇副作用发生的一个因素。
J Clin Endocrinol Metab. 1974 Mar;38(3):407-12. doi: 10.1210/jcem-38-3-407.
4
Prednisone side-effects and serum-protein levels. A collaborative study.泼尼松的副作用与血清蛋白水平。一项合作研究。
Lancet. 1971 Oct 9;2(7728):778-80. doi: 10.1016/s0140-6736(71)92738-3.
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In-patient prescribing in a rheumatic diseases centre. A study in self-abasement.一家风湿病中心的住院处方。一项关于自卑的研究。
Health Bull (Edinb). 1975 Mar;33(2):72-5.
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