Rothhammer A, Weis K H, Skrobek W, Schmidt E, Bruch P, Trenkel K
Anaesthesist. 1981 Sep;30(9):472-5.
Isolated human taenia libera shows spontaneous motility in the organ bath. The active basal tone, force development and frequency of spontaneous contractions and total power parameter "Montevideo Units" were first analysed under control conditions. Halothane lowered the active basal tone, frequency and the total power of the muscle strip in a dose-dependent manner. The amplitude and force of contraction of human taenia libera first began to increase under halothane, attaining its maximum at 1.0 vol.%. Halothane concentrations above 1.5 vol.% at first caused a depression and finally abolished spontaneous motility. The changes in the spontaneous motility pattern brought about by halothane were completely reversible. Possible causes for the halothane effect were considered as to the possible relevance to the in vivo situation.
分离出的人体游离绦虫在器官浴中表现出自发运动。首先在对照条件下分析了主动基础张力、力量发展、自发收缩频率以及总功率参数“蒙得维的亚单位”。氟烷以剂量依赖性方式降低了肌肉条带的主动基础张力、频率和总功率。人体游离绦虫的收缩幅度和力量在氟烷作用下首先开始增加，在1.0体积%时达到最大值。高于1.5体积%的氟烷浓度起初引起抑制，最终消除自发运动。氟烷引起的自发运动模式变化是完全可逆的。考虑了氟烷效应的可能原因及其与体内情况的可能相关性。
