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细胞构筑学的定量方法。VII. 豚鼠皮层的区域模式。

A quantitative approach to cytoarchitectonics. VII. The areal pattern of the cortex of the Guinea pig.

作者信息

Wree A, Zilles K, Schleicher A

出版信息

Anat Embryol (Berl). 1981;162(1):81-103. doi: 10.1007/BF00318096.

DOI:10.1007/BF00318096
PMID:7283175
Abstract

The cerebral cortex of the guinea pig has been examined by means of a quantitative cytoarchitectonic method (Schleicher et al. 1978; Zilles et al. 1978a). In this method, a computer-controlled automatic image analyzer determines the grey level index of microscopic fields measuring 50 X 50 mu m in Nissl-stained sections by a systematic scanning procedure. Computer plots of serially sectioned histological slides from three hemispheres were produced by printing selected ranges of grey level indices. The delineation of cortical areas was worked out in these plots based on quantitative criteria. Cortical maps of the areal pattern were reconstructed graphically. The resulting cortical map of the guinea pig differs from that of Rose (1912), but it corresponds to the results of Friede (1960) and is in agreement with neurophysiological studies. In general, the areal pattern of the guinea pig is similar to that of the rat (Zilles et al. 1980), but there are also some differences. These differences are discussed with respect to functional considerations.

摘要

采用定量细胞构筑学方法(施莱歇尔等人,1978年;齐勒斯等人,1978年a)对豚鼠的大脑皮层进行了研究。在该方法中,计算机控制的自动图像分析仪通过系统扫描程序,测定尼氏染色切片中50×50微米微观视野的灰度指数。通过打印选定的灰度指数范围,生成了来自三个半球的连续切片组织学幻灯片的计算机绘图。基于定量标准,在这些绘图中确定了皮层区域的划分。以图形方式重建了区域模式的皮层图谱。所得的豚鼠皮层图谱与罗斯(1912年)的不同,但与弗里德(1960年)的结果相符,且与神经生理学研究一致。总体而言,豚鼠的区域模式与大鼠的相似(齐勒斯等人,1980年),但也存在一些差异。从功能方面对这些差异进行了讨论。

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