Non-endocrine carcinoid tumour of the uterine cervix: aspects of diagnosis and treatment. Case report.

A case of primary well-differentiated carcinoid tumour of the uterine cervix in a Chinese woman of 62 years without endocrine symptoms is reported and its clinico-pathological features, ultrastructure and response to radiotherapy discussed. To our knowledge, it is the first of such cases seen in Hong Kong. Clinically, it presented as a polypoid lesion. The initial diagnosis was squamous carcinoma of cervix stage Ib and the patient was treated with radiotherapy. The tumour disappeared after application of first intracavitary irradiation of 4500 mg h. After completion of 9000 mg h, Wertheim hysterectomy followed and no residual tumour was found. Retrospective staining of the pre-irradiation cervical tumour by Grimelius method was positive for argyrophil granules and electron microscopic study demonstrated neurosecretory granules in the cytoplasm and established the diagnosis.