Kirkham T H, Coupland S G
Can J Neurol Sci. 1981 Aug;8(3):243-8. doi: 10.1017/s0317167100043274.
Visual function is usually considered to be normal in papilledema. We report previously undescribed abnormalities in the electroretinograms (ERG) and visual evoked potentials (VEP) of two patients with chronic papilledema. The steady-state latencies of the ERG and VEP were calculated using time-difference analysis. The ERG was abnormal under both scotopic (slow) and photopic (fast) flicker conditions, but the VEP was abnormal only to fast flicker photopic stimulation. This may indicate a relative vulnerability of a high frequency signal system under conditions of raised intracranial pressure. The abnormalities resolved rapidly once the intracranial pressure had been normalised. The cause of the VEP and particularly the ERG abnormalities remains unknown.
视乳头水肿时视觉功能通常被认为是正常的。我们报告了两名慢性视乳头水肿患者的视网膜电图（ERG）和视觉诱发电位（VEP）中先前未描述的异常情况。使用时差分析计算ERG和VEP的稳态潜伏期。在暗视（慢）和明视（快）闪烁条件下ERG均异常，但VEP仅在快闪烁明视刺激时异常。这可能表明在颅内压升高的情况下高频信号系统相对脆弱。一旦颅内压恢复正常，这些异常就迅速消失。VEP尤其是ERG异常的原因仍然未知。
