Bobak P, Bodis-Wollner I, Harnois C, Maffei L, Mylin L, Podos S, Thornton J
Am J Ophthalmol. 1983 Jul;96(1):72-83. doi: 10.1016/0002-9394(83)90457-9.
Steady-state visual-evoked potentials and electroretinograms were simultaneously recorded in four patients with glaucoma and in five patients with multiple sclerosis. The stimuli included a homogenous field and a 2.3 cycles per degree sinusoidal grating that were counter-phase modulated at the rate of 7.5 Hz. We used narrow bandwidth spectral analysis to measure the response amplitudes and signal-to-noise ratios. Transient pattern visual-evoked potentials (1 Hz) were also measured for latency in each eye. We found abnormal pattern electroretinograms, based on the absence of a significant second harmonic component, in three of the four glaucomatous eyes although the homogenous field electroretinograms were normal. In the patients with multiple sclerosis, the pattern electroretinograms were abnormal in two eyes, but the transient visual-evoked potential latency had the highest diagnostic yield (seven of ten eyes).
在4例青光眼患者和5例多发性硬化症患者中同时记录稳态视觉诱发电位和视网膜电图。刺激包括一个均匀视野和一个每度2.3周的正弦光栅，以7.5Hz的速率进行反相调制。我们使用窄带频谱分析来测量反应幅度和信噪比。还测量了每只眼睛的瞬态图形视觉诱发电位（1Hz）的潜伏期。我们发现，在4只青光眼眼中，有3只尽管均匀视野视网膜电图正常，但基于显著的二次谐波成分缺失，其图形视网膜电图异常。在多发性硬化症患者中，2只眼睛的图形视网膜电图异常，但瞬态视觉诱发电位潜伏期的诊断率最高（10只眼中有7只）。
