聚二甲基硅氧烷膜血液相容性研究中红外光谱与血小板形态的相关性

Correlation of infrared spectroscopy with platelet morphology in blood compatibility studies of polydimethylsiloxane membranes.

作者信息

Kennedy J H, Ishida H, Staikoff L S, Lewis C W

出版信息

Biomater Med Devices Artif Organs. 1978;6(3):215-24. doi: 10.3109/10731197809118702.

DOI:10.3109/10731197809118702

Abstract

Oxygenator membranes, polydimethylsiloxane elastomer, exposed to flowing heparinized canine blood in a perfusion system have been studied with respect to the platelet activation and the morphology of the membranes. Utilizing Fourier transform infrared spectroscopy couple with attenuated total reflection technique (ATR) and laser Raman spectroscopy, no obvious differences in morphology and composition of the membranes have been detected while electron microscopic study shows difference in platelet aggregation.

摘要

在灌注系统中，将聚二甲基硅氧烷弹性体氧合器膜暴露于流动的肝素化犬血中，对其血小板活化和膜形态进行了研究。利用傅里叶变换红外光谱结合衰减全反射技术（ATR）和激光拉曼光谱，未检测到膜的形态和组成有明显差异，而电子显微镜研究显示血小板聚集存在差异。