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[动物机体水合与脱水对下丘脑前部神经分泌细胞生物能量及介质过程的影响]

[Effect of hydration and dehydration of the bodies of animals on bioenergetic and mediator processes in the neurosecretory cells of the anterior hypothalamus].

作者信息

Mikhaĭlik T A

出版信息

Biull Eksp Biol Med. 1978 Dec;86(12):734-7.

PMID:728622
Abstract

Activity of redox enzymes, and of mediator-inactivated enzymes in the neurosecretory cells of the anterior hypothalamus under hydration and dehydration conditions of the rabbit organism was investigated by the histochemical methods. The activity of the Krebs' cycle enzymes and of the electron transport system responded by an increased activity to dehydration and by decreased one to hydration. The activity of alpha-glycerophosphate dehydrogenase and glucose-6-phosphate dehydrogenase increased as compared to the control in both cases. Changes in the monoamine oxidase activity diminished in dehydration and rose in hydration. As to acetylcholinesterase -- the changes in its activity had a reciprocal character.

摘要

采用组织化学方法,研究了家兔机体在水合和脱水条件下,下丘脑前部神经分泌细胞中氧化还原酶以及被介质灭活的酶的活性。三羧酸循环酶和电子传递系统的活性在脱水时升高,在水合时降低。在这两种情况下,α-甘油磷酸脱氢酶和葡萄糖-6-磷酸脱氢酶的活性均高于对照组。脱水时单胺氧化酶活性的变化减小,水合时升高。至于乙酰胆碱酯酶,其活性变化具有相反的特征。

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