Srivastava U K
Indian J Physiol Pharmacol. 1981 Apr-Jun;25(2):158-62.
Bilateral insertion of silastic capsules releasing 38-44 micrograms norethisterone enanthate/24 h into the epididymal fat-pads was found to induce complete azoospermia leading to infertility in adult male rabbits 8 weeks after insertion of the progestin implants. The treatment did not exert any inhibitory effects on the libido and sexual behaviour of the animals as judged by objective parameters of mating. Further, the failure of the hormone-releasing implants was not found to exert any adverse effects on the embryos and pregnancy as indicated by the delivery of normal pups to females mated with implant-bearing males 3 weeks after the insertion of 'epididymal' implants.
在成年雄性兔子的附睾脂肪垫中双侧植入每24小时释放38 - 44微克庚酸炔诺酮的硅橡胶胶囊，发现植入孕激素植入物8周后会导致完全无精子症，从而使成年雄性兔子不育。根据交配的客观参数判断，该治疗对动物的性欲和性行为没有任何抑制作用。此外，如在“附睾”植入物插入3周后，与植入植入物的雄性交配的雌性产下正常幼崽所示，激素释放植入物的失效未对胚胎和妊娠产生任何不利影响。
