Gozzo S, Di Felice M, Salvati S
Int J Neurosci. 1981;13(4):219-27. doi: 10.3109/00207458108985805.
Several ontogenetic aspects of the cerebral cortex were studied in rats whose mothers were fed on a diet, the lipid fraction of which was extracted from yeast (Candida lipolytica) grown on N-alkanes, during part of pregnancy and throughout lactation. Measures of the heights of some cortical regions and specific layers, the maturation of mean cell volumes and of the cell/gray coefficient, especially in layers I, IV and VI, show that the diet affects cerebral cortex ontogeny. These effects on brain ontogeny and on intrinsic and extrinsic neuron connections may explain the electrophysiological and behavioural alterations observed in previous studies.
在大鼠中研究了大脑皮质的几个个体发育方面,这些大鼠的母亲在部分孕期和整个哺乳期被喂食一种饮食,该饮食的脂质部分是从在正构烷烃上生长的酵母(解脂假丝酵母)中提取的。对一些皮质区域和特定层的高度、平均细胞体积以及细胞/灰质系数的成熟度(尤其是在第I、IV和VI层)的测量表明,这种饮食会影响大脑皮质的个体发育。这些对脑个体发育以及内在和外在神经元连接的影响,可能解释了先前研究中观察到的电生理和行为改变。