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由含有从以正构烷烃为生长底物培养的酵母(解脂假丝酵母)中提取的脂质部分的饮食所引起的大鼠大脑皮质个体发育变化。

Ontogenetic alterations of the cerebral cortex in rat caused by a diet containing a lipid fraction extracted from yeast (Candida lipolytica) grown on N-alkanes.

作者信息

Gozzo S, Di Felice M, Salvati S

出版信息

Int J Neurosci. 1981;13(4):219-27. doi: 10.3109/00207458108985805.

DOI:10.3109/00207458108985805
PMID:7287322
Abstract

Several ontogenetic aspects of the cerebral cortex were studied in rats whose mothers were fed on a diet, the lipid fraction of which was extracted from yeast (Candida lipolytica) grown on N-alkanes, during part of pregnancy and throughout lactation. Measures of the heights of some cortical regions and specific layers, the maturation of mean cell volumes and of the cell/gray coefficient, especially in layers I, IV and VI, show that the diet affects cerebral cortex ontogeny. These effects on brain ontogeny and on intrinsic and extrinsic neuron connections may explain the electrophysiological and behavioural alterations observed in previous studies.

摘要

在大鼠中研究了大脑皮质的几个个体发育方面,这些大鼠的母亲在部分孕期和整个哺乳期被喂食一种饮食,该饮食的脂质部分是从在正构烷烃上生长的酵母(解脂假丝酵母)中提取的。对一些皮质区域和特定层的高度、平均细胞体积以及细胞/灰质系数的成熟度(尤其是在第I、IV和VI层)的测量表明,这种饮食会影响大脑皮质的个体发育。这些对脑个体发育以及内在和外在神经元连接的影响,可能解释了先前研究中观察到的电生理和行为改变。

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1
Ontogenetic alterations of the cerebral cortex in rat caused by a diet containing a lipid fraction extracted from yeast (Candida lipolytica) grown on N-alkanes.由含有从以正构烷烃为生长底物培养的酵母(解脂假丝酵母)中提取的脂质部分的饮食所引起的大鼠大脑皮质个体发育变化。
Int J Neurosci. 1981;13(4):219-27. doi: 10.3109/00207458108985805.
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Fatty acid composition of adipose tissue and liver fats of the rats fed yeast grown on n-alkanes.以正构烷烃培养的酵母喂养的大鼠的脂肪组织和肝脏脂肪的脂肪酸组成。
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[Effect of temperature and nitrogen source on lipid biosynthesis by yeast grown on n-alkanes].[温度和氮源对以正构烷烃为碳源生长的酵母脂质生物合成的影响]
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[Higher fatty acids of Candida lipolytica grown in n-alkanes by the industrial method ("Toprina")].[通过工业方法(“Toprina”)在正构烷烃中培养的解脂耶氏酵母的高级脂肪酸]
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[State of the Na+, K+-ATPase system of the female rat brain cerebral cortex in the postnatal period during ethanol consumption in pregnancy and lactation].[孕期和哺乳期乙醇摄入期间雌性大鼠脑皮质钠钾-ATP酶系统在出生后阶段的状态]
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