Parish E J, Schroepfer G J
J Lipid Res. 1981 Jul;22(5):859-68.
A simplified method is described for the preparation of 14 alpha-hydroxymethyl-4,4-dimethyl-5 alpha-cholest-8-en-e beta-ol, 14 alpha-hydroxymethyl-4,4-dimethyl-5 alpha-cholest-7-en-3 beta-ol, and 14 alpha-hydroxymethyl-4,4-dimethyl-5-alpha-cholest-6-en-3 beta-ol from commercial lanosterol. This method represents a modification of the approach introduced by Fried and co-workers (Fried, J., J. W. Brown, and L. Borkenhagen. 1965. Tetrahedron Lett. 2499-2504).
描述了一种从市售羊毛甾醇制备14α-羟甲基-4,4-二甲基-5α-胆甾-8-烯-3β-醇、14α-羟甲基-4,4-二甲基-5α-胆甾-7-烯-3β-醇和14α-羟甲基-4,4-二甲基-5α-胆甾-6-烯-3β-醇的简化方法。该方法是对Fried及其同事(Fried, J., J. W. Brown, and L. Borkenhagen. 1965. Tetrahedron Lett. 2499 - 2504)所引入方法的改进。