一个家族的三名成员患有多发性原发性恶性肿瘤。
Multiple primary malignant neoplasia in three members of a family.
作者信息
Kenyon G S
出版信息
J R Soc Med. 1981 Aug;74(8):601-4. doi: 10.1177/014107688107400809.
Abstract
Three members of a family have presented in adult life with a succession of invasive malignancies. No known premalignant condition has been apparent in this group, and a limited study of immune competence has failed to reveal any abnormality. In spite of this there is strong evidence to suggest a so far undetected immunogenetic abnormality as the basis of this phenomenon.
摘要
一个家庭中的三名成员在成年后相继患上侵袭性恶性肿瘤。在这个群体中，没有明显的已知癌前病变，对免疫功能的有限研究也未发现任何异常。尽管如此，有强有力的证据表明，一种迄今未被发现的免疫遗传异常是这一现象的基础。
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