Soskolne W A
Cell Tissue Res. 1978 Dec 29;195(3):557-64. doi: 10.1007/BF00233897.
The osteoclast-osteocyte relationship at the endosteal surface of femora of two-week old rabbits was studied. Light microscopic observations suggest that during physiological resorption phagocytosis by osteoclasts of osteocytes takes place. Serial sections confirm that the cells are totally engulfed within the cytoplasm of the osteoclasts. Ultrastructural studies support these findings and indicate that the initial stage of phagocytosis of the osteocytes consists of the insinuation of an extnesion of the ruffled border into the osteocyte lacuna. These extensions are seen to make close contact with the osteocytes prior to their engulfment by the osteoclasts and their final digestion within phagosomes.
研究了两周龄兔子股骨骨内膜表面破骨细胞与骨细胞的关系。光学显微镜观察表明，在生理性吸收过程中，破骨细胞会对骨细胞进行吞噬作用。连续切片证实这些细胞完全被吞噬进破骨细胞的细胞质中。超微结构研究支持了这些发现，并表明骨细胞吞噬作用的初始阶段包括褶皱缘的延伸插入骨细胞腔隙。在这些延伸被破骨细胞吞噬并在吞噬体内最终消化之前，可以看到它们与骨细胞紧密接触。
