Warwas M, Dobryszycka W, Gerber J, Pietkiewicz A
Neoplasma. 1981;28(4):485-90.
Concentrations of the following acute-phase reactants (APR) were determined in the sera of patients with benign and malignant ovarian tumors: haptoglobin, ceruloplasmin, sialic acid, seromucoid (in sulphosalicylic acid supernatant), and trypsin inhibitory capacity. In patients with ovarian carcinomas significant increase (p less than 0.001) in all measured APR parameters as compared to healthy women and women with benign tumors was found. Moreover, the levels of haptoglobin, ceruloplasmin and trypsin inhibitory capacity were statistically lower (p less than 0.001) in nonmalignant than in malignant ovarian disease. No distinct statistical difference was confirmed between healthy controls and the benign tumor group as well as between ovarian carcinomas of Stages I--III and Stage IV.
在患有良性和恶性卵巢肿瘤的患者血清中测定了以下急性期反应物（APR）的浓度：触珠蛋白、铜蓝蛋白、唾液酸、血清类粘蛋白（磺基水杨酸上清液中）和胰蛋白酶抑制能力。与健康女性和患有良性肿瘤的女性相比，发现卵巢癌患者所有测量的APR参数均显著升高（p<0.001）。此外，非恶性卵巢疾病中触珠蛋白、铜蓝蛋白和胰蛋白酶抑制能力的水平在统计学上低于恶性卵巢疾病（p<0.001）。健康对照组与良性肿瘤组之间以及I-III期和IV期卵巢癌之间未证实有明显的统计学差异。
