Earlbaum A M, Quinton P M
Nephron. 1981;28(2):58-61. doi: 10.1159/000182107.
Mg and PO4 concentrations were significantly higher in unmixed parotid saliva from chronic renal failure (CFR) patients than in controls. No significant differences were noted in the flow, pH or concentrations of Na, K, Cl or Ca; however, the Na/K ratio was significantly lower in CRF patients. No correlation between plasma PTH levels and the concentrations of Ca, Mg, or PO4 in saliva was found. Taken with previous results from elevated divalent ion concentrations in sweat from CRF patients, these findings suggest that the excretion of divalent electrolyte glands may represent a generalized abnormality in exocrine glands in CRF. We hypothesize that the active processes involved in regulating the concentrations of these ions in exocrine secretions are altered so that larger amounts of these elements are excreted in CRF patients.
慢性肾衰竭（CFR）患者未混合腮腺唾液中的镁和磷酸根浓度显著高于对照组。在流量、pH值或钠、钾、氯或钙的浓度方面未发现显著差异；然而，CRF患者的钠/钾比值显著较低。未发现血浆甲状旁腺激素水平与唾液中钙、镁或磷酸根浓度之间存在相关性。结合之前CRF患者汗液中二价离子浓度升高的结果，这些发现表明二价电解质腺体的排泄可能代表了CRF患者外分泌腺的普遍异常。我们推测，调节外分泌分泌物中这些离子浓度的活跃过程发生了改变，从而使得CRF患者排泄出更多量的这些元素。
