Handa S P, Tewari H D
Nephron. 1981;28(2):62-4. doi: 10.1159/000182109.
In 19 patients with analgesic nephropathy followed at 6- to 8- month intervals during the past 8 years (average follow-up time 5.1 years), 2 patients developed cancer of the urinary tract. Both patients had heavy consumption of analgesic for more than 25 years, however, they had stopped its use 4 and 8 years ago, respectively. The incidence of bladder tumors in the province of New Brunswick is noted to be 28 per 100,000 population for 5 years. The occurrence of carcinoma in 2 patients in a group of 19 patients with analgesic abuse suggests an association.
在过去8年中，对19例镇痛剂肾病患者进行了为期6至8个月的随访（平均随访时间5.1年），其中2例患者发生了泌尿系统癌症。两名患者均大量服用镇痛剂超过25年，但他们分别在4年前和8年前停止了服用。新不伦瑞克省膀胱肿瘤的发病率据记录为每10万人口5年中有28例。在19例滥用镇痛剂的患者中有2例发生癌症，这表明存在某种关联。
