Barthelemy M, Barthelemy A, Naret C, Ciancioni C, Caquet R, Delons S
Nephrologie. 1981;2(2):67-72.
M. mode echocardiography was performed on 16 chronic hemodialysis patients (12 men, 4 women, average use of 21, hematocrit around 24 +/- 5%) with a normal blood pressure and no clinical or roentgenographic signs of heart failure, 18 to 22 hours after the end of a dialysis. Renal diseases due to hypertension, diabetes or amyloidosis were excluded from the study. 8 normal subjects of similar age, heart rate and blood pressure were used as a test group. On these 24 persons, and diastolic time diameter index (DTDI) and end systolic time diameter index (STDI), ejection time (ET), mean velocity of circumferential fiber shortening (VCF) and ejection fraction were calculated. DTDI of hemodialysis patients (31 mm/m(2) +/- 2) is greater than DTDI of the control subjects, and STDI and ET are the same. This explains the increase of VCF (1,69 +/- 0,10 c/s) and EF (0,78 +/- 0,05). After a three minute compression of the fistulas the differences disappear. These results suggest that the previous exam conditions permit a better determination of the true contractile state of the left ventricule of hemodialyzed patients if one disregards the load changes due to the fistula, anemia and the intermittent volume expansion.
对16名慢性血液透析患者(12名男性,4名女性,平均透析时间21小时,血细胞比容约为24±5%)在透析结束后18至22小时进行了M型超声心动图检查,这些患者血压正常,无心力衰竭的临床或X线征象。研究排除了由高血压、糖尿病或淀粉样变性引起的肾脏疾病。选取8名年龄、心率和血压相似的正常受试者作为对照组。对这24人计算了舒张期时间直径指数(DTDI)、收缩末期时间直径指数(STDI)、射血时间(ET)、圆周纤维缩短平均速度(VCF)和射血分数。血液透析患者的DTDI(31mm/m²±2)大于对照组,而STDI和ET相同。这解释了VCF(1.69±0.10c/s)和EF(0.78±0.05)的增加。在对动静脉内瘘压迫三分钟后,差异消失。这些结果表明,如果不考虑动静脉内瘘、贫血和间歇性容量扩张引起的负荷变化,先前的检查条件能够更好地确定血液透析患者左心室的真实收缩状态。