Thomas J R, Schrot J, Banvard R A
Neurobehav Toxicol. 1980 Summer;2(2):131-5.
Previous research findings on the interaction between drugs and microwave radiation were extended to chlorpromazine and to diazepam. The drugs were combined with a 1 mW/cm2 pulsed microwave field (2.8 GHz) and effects were measured on a fixed interval (FI 1) schedule of food reinforcement with rats. Dose-effect functions with and without sham irradiation were established for each drug. At effective doses chlorpromazine consistently decreased rate of responding and reduced with-interval response patterning. Low to moderate doses of diazepam produced little change or increases in response rate, and higher doses produced a decline in response rate. Response patterning within intervals was reduced by increasing doses of diazepam. The animals were exposed to the microwave field alone before test sessions combining the drugs with microwave radiation. Microwave exposure alone did not affect FI performance. Microwave radiation in combination with either drug did not produce any alterations in the dose-effect functions.
先前关于药物与微波辐射相互作用的研究结果扩展至氯丙嗪和地西泮。将这些药物与1毫瓦/平方厘米的脉冲微波场（2.8吉赫兹）相结合，并在大鼠的固定间隔（FI 1）食物强化程序中测量其效果。针对每种药物建立了有无假照射情况下的剂量效应函数。在有效剂量下，氯丙嗪持续降低反应速率并减少间隔内的反应模式。低至中等剂量的地西泮对反应速率几乎没有影响或使其增加，而高剂量则导致反应速率下降。随着地西泮剂量增加，间隔内的反应模式减少。在将药物与微波辐射结合的测试环节之前，先让动物单独暴露于微波场中。单独的微波暴露不影响固定间隔程序的表现。微波辐射与任何一种药物联合使用时，剂量效应函数均未产生任何改变。
