Cohen-Boulakia F, Mazière B, Comar D
Phys Med Biol. 1981 Sep;26(5):857-65. doi: 10.1088/0031-9155/26/5/005.
Sodium kinetics were studied in the hands of 14 subjects by local in vivo neutron activation analysis. Hands were irradiated with 252 Cf sources giving absorbed doses of 8 cGy. The variation in 24Na radioactivity was plotted against time, and each curve fitted to a function that was the sum of two exponentials. Two pools were identified, one corresponding to fast turnover, with a half-life of about one hour, the other to a slower turnover process with a half-life averaging 79 h if the calcium concentration of the hand bones is normal, and 35 h if it is subnormal. The mean ratio of calcium to slowly exchangeable sodium is estimated to be 47.7, and the ratio of quickly exchangeable sodium to slowly exchangeable sodium to be 0.65. These various parameters should be of interest in bone pathology.
通过局部体内中子活化分析研究了14名受试者手部的钠动力学。用252 Cf源对手部进行照射，吸收剂量为8 cGy。绘制24Na放射性随时间的变化曲线，每条曲线拟合为两个指数之和的函数。确定了两个池，一个对应快速周转，半衰期约为1小时，另一个对应较慢的周转过程，如果手部骨骼钙浓度正常，半衰期平均为79小时，如果钙浓度低于正常水平，则为35小时。钙与慢交换钠的平均比值估计为47.7，快交换钠与慢交换钠的比值为0.65。这些不同的参数在骨病理学中应具有重要意义。
