Spinks T J, Bewley D K, Joplin G F, Ranicar A S
J Nucl Med. 1976 Aug;17(8):724-9.
Turnover of sodium in the human hand was studied by neutron activation. One hand of each subject was irradiated with a 1.5-rad dose of partially thermalized fast neutrons. The activity of 24Na was measured at intervals from 3 min to 48 hr after irradiation. The loss of sodium from the hand during this period can be described either by two exponentials or by a single power function. The latter description involves only two disposable factors compared with four in the former. The rate of loss of sodium was found, on the average, to be greater in patients suffering from bone disease than in normal subjects. Neutron activation is a powerful method for studying sodium turnover because the sodium atoms are labeled simultaneously and with equal probability, regardless of the turnover time of individual bodily compartments.
通过中子活化研究了人体手部钠的周转率。对每位受试者的一只手用1.5拉德剂量的部分热化快中子进行照射。在照射后3分钟至48小时的间隔内测量24Na的活性。在此期间手部钠的流失可用两个指数函数或一个单一幂函数来描述。与前者的四个相比，后者的描述仅涉及两个任意因子。结果发现，平均而言，患有骨病的患者钠的流失率高于正常受试者。中子活化是研究钠周转率的一种有力方法，因为钠原子被同时且以相等的概率标记，而与各个身体腔室的周转时间无关。
