文献检索，用中文搜 PubMed

Suppr 超能文献

核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Mukhtar H, Baars A J, Breimer D D

Xenobiotica. 1981 Jun;11(6):367-71. doi: 10.3109/00498258109045847.

Rat liver mitochondrial microsomal glutathione (GSH) S-transferase activities with 1-chloro-2,4-dinitrobenzene as substrate were 11.0 and 11.6%, and with 1,2-dichloro-4-nitrobenzene as substrate were 27.7 and 15.4%, of the corresponding cytosolic activities respectively. 2. Marked difference in inducibility of cytosolic and particulate GSH S-transferase activities were seen after pretreatment of animals with enzyme-inducing agents. 3-Methylcholanthrene and 2,3,7,8-tetrachlorodibenzo-p-dioxin enhanced cytosolic GSH S-transferase activity only. Phenobarbital induced the cytosolic and microsomal enzymes only.

以1-氯-2,4-二硝基苯为底物时，大鼠肝脏线粒体微粒体谷胱甘肽（GSH）S-转移酶的活性分别为相应胞质活性的11.0%和11.6%；以1,2-二氯-4-硝基苯为底物时，其活性分别为相应胞质活性的27.7%和15.4%。2. 用酶诱导剂预处理动物后，胞质和微粒体GSH S-转移酶活性的诱导性存在显著差异。3-甲基胆蒽和2,3,7,8-四氯二苯并对二恶英仅增强胞质GSH S-转移酶活性。苯巴比妥仅诱导胞质和微粒体酶。

Mukhtar H, Baars A J, Breimer D D

Xenobiotica. 1981 Jun;11(6):367-71. doi: 10.3109/00498258109045847.

Rat liver mitochondrial microsomal glutathione (GSH) S-transferase activities with 1-chloro-2,4-dinitrobenzene as substrate were 11.0 and 11.6%, and with 1,2-dichloro-4-nitrobenzene as substrate were 27.7 and 15.4%, of the corresponding cytosolic activities respectively. 2. Marked difference in inducibility of cytosolic and particulate GSH S-transferase activities were seen after pretreatment of animals with enzyme-inducing agents. 3-Methylcholanthrene and 2,3,7,8-tetrachlorodibenzo-p-dioxin enhanced cytosolic GSH S-transferase activity only. Phenobarbital induced the cytosolic and microsomal enzymes only.

以1-氯-2,4-二硝基苯为底物时，大鼠肝脏线粒体微粒体谷胱甘肽（GSH）S-转移酶的活性分别为相应胞质活性的11.0%和11.6%；以1,2-二氯-4-硝基苯为底物时，其活性分别为相应胞质活性的27.7%和15.4%。2. 用酶诱导剂预处理动物后，胞质和微粒体GSH S-转移酶活性的诱导性存在显著差异。3-甲基胆蒽和2,3,7,8-四氯二苯并对二恶英仅增强胞质GSH S-转移酶活性。苯巴比妥仅诱导胞质和微粒体酶。