Bunegin L, Albin M S, Helsel P E, Hoffman A, Hung T K
Anesthesiology. 1981 Oct;55(4):343-8. doi: 10.1097/00000542-198110000-00003.
A flexible Silastic casting of the human right atrium was developed to correspond to some in vivo human right atrium hemodynamic characteristics including chamber pressures, pulsatility, fluid output, and flow velocity. Using an infusion pump, air was introduced (10 ml in 30 s) into the superior vena cava of the model and aspirated via a catheter from different positions within the model atrial chamber. The tests were carried out at atrial inclinations of 60 degrees, 80 degrees, and 90 degrees from the horizontal and compared the aspiration efficiency of a single-orificed 16-gauge catheter to a 16-gauge multiorified (5 aperatures) catheter. Optimal air aspiration occurred with the multiorificed catheter tip positioned within the area 2.0 cm below the junction of the superior vena cava (SVC) and the atrial chamber at an inclination of 80 degrees. As much as 80 per cent of the incoming air could be aspirated under these conditions. At its optimal position the single-orificed catheter gave a maximal yield of 45 to 50 per cent aspiration when the tip was positioned 3.0 cm above the SVC and atrial chamber junction. Aspiration of air from mid right atrium (4.5 cm below the SVC-atrial junction) was poor regardless of the type of catheter used or atrial inclination. These data suggest a need for reappraisal of catheter design and placement.
开发了一种与人体右心房体内某些血流动力学特征相对应的柔性硅橡胶右心房模型,这些特征包括腔室压力、搏动性、液体输出和流速。使用输液泵,将空气(30秒内注入10毫升)引入模型的上腔静脉,并通过导管从模型心房内的不同位置吸出。在模型心房与水平方向呈60度、80度和90度倾斜的情况下进行测试,并比较了单孔16号导管与16号多孔(5个孔)导管的抽吸效率。当多孔导管尖端位于上腔静脉(SVC)与心房腔交界处下方2.0厘米区域内且倾斜度为80度时,空气抽吸效果最佳。在这些条件下,多达80%的进入空气可以被吸出。在其最佳位置,当单孔导管尖端位于SVC与心房腔交界处上方3.0厘米时,最大抽吸率为45%至50%。无论使用何种类型的导管或心房倾斜度如何,从右心房中部(SVC - 心房交界处下方4.5厘米)抽吸空气的效果都很差。这些数据表明需要重新评估导管的设计和放置。