Pförringer W, Rosemeyer B, Bassermann R, Löppert M
Arch Orthop Trauma Surg (1978). 1981;98(2):85-91. doi: 10.1007/BF00460794.
Surface replacement of the hip has been performed in 25 rabbits. Twenty animals were chosen for evaluation of the result of the operation after an average period of five months postoperatively. Tetracycline injections were given for fluorochrome labeling and radiographic controls have been made in vivo to check the position of the cup before the animals were sacrificed. Histological examinations were made from slides, which were gained after the metal cup had been removed with the bone cement still in place. It was found that the bone underneath the cup survived the surface replacement and that there was a normal metabolism further on. The trabeculae even grew into the surface structures of the inner layer of the bone cement and there was no interposition of membranes of fibrous tissue. It could be demonstrated that fibrous tissue between bone and bone cement is found only in cases of loosening of the cup and the cement or in cases of insufficient contact between this interface from the moment of the operation on. This is possible when air bubbles arise in the bone cement and get in contact with the trabeculae of the femoral head. Fluorochrome labeling proved the formation of new bone underneath the cup and the survival of the osseous structures of the coxal end of the femur. We believe, that in clinical cases it is necessary to remove all predamaged cancellous bone from the head of the femur (i.e. in cases of avascular necrosis) before the cup is attached. Close contact between the bone cement and the healthy spongiosa is one of the conditions for success in surface replacement of the hip.
对25只兔子进行了髋关节表面置换术。平均术后五个月后,选择20只动物评估手术结果。注射四环素进行荧光色素标记,并在体内进行X线对照检查,以在处死动物前检查髋臼的位置。组织学检查是从在金属髋臼已被移除而骨水泥仍留在原位后获得的切片进行的。结果发现,髋臼下方的骨在表面置换后存活下来,并且后续有正常的代谢。骨小梁甚至长入骨水泥内层的表面结构,并且没有纤维组织膜的插入。可以证明,仅在髋臼和骨水泥松动的情况下,或者从手术时起该界面之间接触不充分的情况下,才会在骨与骨水泥之间发现纤维组织。当骨水泥中出现气泡并与股骨头的骨小梁接触时,就会出现这种情况。荧光色素标记证明了髋臼下方新骨的形成以及股骨髋臼端骨结构的存活。我们认为,在临床病例中,在安装髋臼之前,有必要从股骨头(即缺血性坏死病例)去除所有预先受损的松质骨。骨水泥与健康松质骨之间的紧密接触是髋关节表面置换成功的条件之一。