给怀孕小鼠口服乙醇后，乙醇进入胎儿和羊水的途径。
The passage to the foetus and liquor amnii of ethanol administered orally to the pregnant mouse.
作者信息
Kaufman M H, Woollam D H
出版信息
Br J Exp Pathol. 1981 Aug;62(4):357-61.
The relationship between the time of oral administration of a dilute aqueous solution of ethanol and its concentration in the blood and urine was determined in a group of non-pregnant mice. The ethanol concentration was also determined in the maternal blood, foetuses and liquor amnii in female mice to which ethanol had been administered on the 18th day of pregnancy. In the pregnant females peak ethanol levels were achieved first in the maternal blood, then in the foetuses and slightly later in the amniotic fluid. Unilateral ligation of the uterine vessels markedly delayed the amount of ethanol reaching the foetuses and liquor. The present experimental system may provide a model for the human phenomenon of "binge" drinking.
在一组未怀孕的小鼠中测定了口服稀乙醇水溶液的时间与其在血液和尿液中的浓度之间的关系。还测定了在怀孕第18天给予乙醇的雌性小鼠的母血、胎儿和羊水中的乙醇浓度。在怀孕的雌性小鼠中，乙醇水平首先在母血中达到峰值，然后在胎儿中达到峰值，羊水峰值出现稍晚。单侧结扎子宫血管显著延迟了到达胎儿和羊水的乙醇量。目前的实验系统可能为人类“暴饮”现象提供一个模型。
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