Sonkodi S, Nicholls M G, Cumming A M, Robertson J I
Clin Endocrinol (Oxf). 1981 Jun;14(6):613-20. doi: 10.1111/j.1365-2265.1981.tb02972.x.
We observed that change in body posture from the supine to the erect position in normal volunteers was associated with a rise in circulating potassium and a fall in sodium concentrations, irrespective of whether the electrolytes were measured in serum or plasma, or whether head-up tilt or ambulation was used. In patients with primary aldosteronism, the fall in serum sodium and rise in serum potassium with ambulation tended to obscure the characteristic electrolyte abnormalities of that syndrome. These changes in potassium and sodium could contribute to the rise in aldosterone secretion on orthostasis. The body posture of patients should be considered in the interpretation of plasma and serum electrolyte levels.
我们观察到，正常志愿者从仰卧位变为直立位时，无论电解质是在血清还是血浆中测量，也无论采用头高位倾斜还是行走方式，循环钾水平都会升高，钠浓度会降低。在原发性醛固酮增多症患者中，行走时血清钠下降和血清钾升高往往会掩盖该综合征典型的电解质异常。钾和钠的这些变化可能导致直立位时醛固酮分泌增加。在解释血浆和血清电解质水平时应考虑患者的体位。
